Turn the PCIe (aka PCI express) slot in your desktop into an ExpressCard slot. After a simple do-it-yourself installation, this adapter will do the rest.
There are certain ExpressCards you need to use with your desktop. Thus, you are in search of this card. As long as your desktop has a PCIe (aka PCI express, or PCI-E) slot, you will be able to use any ExpressCard with your desktop with the aid of this simple adapter that you install yourself.