Add a serial (RS-232) port to your system using an expresscard slot with this serial expresscard from Quatech.
Quatech's Performance Series
This card belongs to Quatech's "Performance Series," promising perfect functionality at faster speeds and efficiency than other card protocols. It also means that it operates based on PCIe power control and design core rather than USB. The PCI-e design allows the card to directly use I/O space addresses and interrupts, thus more closely emulates built-in ports than can be done via USB-based design. Moreover, because there's no USB stack for the drivers to contend with, throughput can be higher and latency will be lower (considerably so in many cases).
Being expresscard-34, this card will work in both expresscard-34 and expresscard-54 slots.